DNA Ancestry Test - 2 Test Combo

Fee Schedule for Year 2022 Order

Test Type Private Test
Standard Combo Ancestry Package (Y-DNA 20 STR Marker + mtDNA HVR1 Test) $238
Standard Combo Ancestry Package (Y-DNA 20 STR Marker + mtDNA HVR1 Test) $238
Advanced Combo Ancestry Package (Y-DNA 44 STR Marker + mtDNA HVR1 + HVR2 Test) $388
Advanced Combo Ancestry Package (Y-DNA 44 STR Marker + mtDNA HVR1 + HVR2 Test) $388
Premium Combo Ancestry Package (Y-DNA 101 STR Marker + mtDNA HVR1 + HVR2 + Coding Region Test) $1779
Premium Combo Ancestry Package (Y-DNA 101 STR Marker + mtDNA HVR1 + HVR2 + Coding Region Test) $1779

All orders received before 3pm PST / 6pm EST are shipped out the same business day. All orders received after 3pm PST / 6pm EST or on weekends or holidays are shipped out the following business day. 24/7 online status check and account management available for all tests.

DNA Ancestry Testing

DNA ancestry testing can help you to trace your paternal and maternal lineages. When you order the test, a buccal swab collection kit is sent to you to collect a DNA sample quickly and painlessly from inside the mouth. The full genetic report is included with every test.

There are two types of DNA Ancestry tests available: Y-DNA STR marker testing for tracing paternal lineage and mtDNA sequencing for tracing maternal lineage. This combo test analyses both Y-DNA and mtDNA from the same DNA sample.

What is Y-DNA?

Y chromosome DNA (Y-DNA) is the DNA found on the Y chromosome, the male sex chromosome. We each have 23 pairs of chromosomes: 22 pairs of autosomal chromosomes and two sex chromosomes – the X and Y chromosomes.

Females inherit two X chromosomes (one from each parent), while males inherit one X chromosome (from their mother) and one Y chromosome (from their father). Therefore, only males have Y-DNA, so only males can take this Y-DNA test.  

Y-DNA is passed down strictly from father to son along the direct paternal line. The patrilineal inheritance pattern of Y-DNA means that all males who descended from the same patrilineal ancestral lineage will have the same (or very similar) Y-DNA profile. Y-DNA testing allows you to trace the ancestry of your direct paternal lineage (your father’s, father’s, father’s… paternal lineage). 

What is a Y-STR test?

A Y-STR test analyzes markers in the Y chromosome known as STRs or ‘short tandem repeats’. STR markers are short segments of DNA (2-13 nucleotides in length), which are repeated multiple times.

STR analyses measure the exact number of repeat units. The number of repeats differs between individuals, because STRs change frequently. Closely related individuals will have similar Y-STR profiles compared to those that do not belong to the same paternal line.

What is mtDNA?

Mitochondrial DNA (mtDNA) is found in the mitochondria of human cells. Each cell can contain several mitochondria, and each mitochondrion contains dozens of copies of mtDNA. So in every cell there can be thousands of copies of mtDNA. This is different from nuclear DNA, since we only inherit two copies of the autosomal and sex chromosomes per cell.

mtDNA is passed down strictly from mother to child along the direct maternal line. The matrilineal inheritance pattern of mtDNA means that all people who descended from the same matrilineal ancestral lineage will have exactly the same mtDNA profile. mtDNA testing allows you to trace the ancestry of your direct maternal lineage (your mother’s, mother’s, mother’s… maternal lineage).

What is mtDNA sequencing?

The circular mitochondrial genome has three regions – two small hypervariable (HVR) regions and a large coding region. It is possible to sequence just the HVR1 region, both hypervariable regions (HVR1 and HVR2), or the complete mitochondrial genome (HVR1, HVR2 and the coding region).

The hypervariable regions comprise approximately 1100 bases of the mtDNA genome. Most of the variation in the mtDNA occurs in these regions. If two people have a perfect match at their HVR1 and HVR2 regions, further analysis of the much larger coding region can provide a higher stringency comparison and further resolution. The coding region covers the remainder of the mitochondrial genome and the complete mitochondrial genome is 16,569 base pairs.

What do you get when you order the 2 test combo?

You will receive a certificate detailing the number of repeats that your carry at each STR marker tested, the genetic sequence of mtDNA region(s) that you have tested and your predicted or confirmed mtDNA Haplogroup. You will also be able to access the following complimentary databases to bring your ancestry to the next level

  1. DNA Reunion database - search for long lost relatives on your direct paternal line
  2. Indigenous DNA database - find out which indigenous population is the closest match to your paternal lineage
  3. DNA Haplogroups database - trace the ancient migration of your paternal ancestors to their final ancestral homeland
  4. Famous DNA database - compare your DNA against famous historical figures

Can females take this ancestry combo test? 

No, only males have Y-DNA so only males can take this combo test, as it analyses both Y-DNA and mtDNA. Females wishing to trace their paternal lineage must test the Y-DNA of a male family member such as a father, brother, male cousin or nephew who is on their direct paternal line. However, both males and females can take the mtDNA to trace their maternal lineage.

If I choose only the Standard Ancestry Combo test, can I test more markers at a later date? 

Yes, if you test 20 STR markers and just the mtDNA HVR1 region in the Standard Ancestry Combo test, you can choose to upgrade to either the Advanced or Premium Ancestry Combo at a later date. However, you may be required to collect a new sample for the additional testing.