Your Alzheimer’s Disease DNA Test Results

Are you at increased risk of developing late-onset Alzheimer’s disease?

Find out if you are at risk - get tested

Test Type Private Test
DNA Paternity Test $150
DNA Paternity Test $245
Cardiovascular Disease Risk Factor (Apolipoprotein E) Genetic Test $195
DNA Nutrition Test $249
DNA Weight Loss Test $249
DNA Fitness Test $249
Nutrition, Weight Loss, Fitness Combo $498
DNA Paternity Test $340
DNA Paternity Test $435
DNA Paternity Test $530
DNA Paternity Test $625
DNA Paternity Test $245
DNA Maternity Test $150
DNA Cardiovascular Health Test $349
DNA Skin Health Test $249
DNA Maternity Test $245
DNA Osteoporosis Risk Test $195
DNA Maternity Test $340
DNA Type 2 Diabetes Risk Test $349
DNA Maternity Test $435
DNA Paternity and Maternity Combo Test $245
Hemochromatosis DNA Test $195
DNA Paternity and Maternity Combo Test $340
Late-Onset Alzheimer's Disease Risk DNA Test $195
DNA Paternity and Maternity Combo Test $435
DNA Paternity and Maternity Combo Test $530
DNA Paternity and Maternity Combo Test $625
DNA Paternity and Maternity Combo Test $720
DNA Thrombotic Risk Test (Includes F2, F5 and MTHFR) $249
DNA Sibling Test $150
Fragile X Syndrome (FMR1) DNA Test $359
Sickle Cell Disease (HbC, HbE and HbS) DNA Test $195
DNA Sibling Test $245
Beta Thalassemia (HBB Gene Sequencing) DNA Test $359
Cystic Fibrosis Mutation Analysis (39 Mutation Panel) DNA Test $359
DNA Sibling Test $340
DNA Sibling Test $435
DNA Sibling Test $530
DNA Sibling Test $625
Ashkenazi Jewish Mutation Panel (10 common disorders, without Cystic Fibrosis) Test $549
DNA Grandmother Test $150
DNA Grandmother Test $245
DNA Alcohol Risk Test $195
DNA Celiac Test $249
DNA Lactose Intolerance Test $129
DNA Caffeine Sensitivity Test $129
DNA Aunt Test $150
DNA Narcolepsy Test $195
Anxiety & Depression DNA Test $119
DNA Warrior Gene Test $119
DNA Cousin Test $150
DNA Warfarin Sensitivity Test $195
DNA Cousin Test $245
DNA Twin Test $150
DNA Twin Test $245
*Standard Paternal Ancestry Package (Y-DNA 20 STR Marker Test) $119
Autosomal DNA STR Marker Test for DNA Reunion $99
DNA Paternity Test (with mother) $245
DNA Paternity Test (with mother) $340
DNA Paternity Test (with mother) $435
DNA Paternity Test (with mother) $530
DNA Paternity Test (with mother) $340
DNA Maternity Test (with Father) $245
Factor II Prothrombin (F2) DNA Test $129
Factor V Leiden (F5) DNA Test $129
Methylenetetrahydrofolate Reductase (MTHFR) DNA Test $129
DNA Sibling Test (with mother) $245
DNA Sibling Test (with mother) $340
Ashkenazi Jewish Mutation Panel (11 common disorders, including Cystic Fibrosis) Test $874
Tay-Sachs Disease DNA Test $195
Niemann-Pick Type A and B DNA Test $195
Mucolipidosis Type IV DNA Test $195
Glycogen Storage Disease Type IA DNA Test $195
Gaucher Disease DNA Test $195
Fanconi Anemia Group C DNA Test $195
Familial Dysautonomia DNA Test $195
Canavan Disease DNA Test $195
Bloom Syndrome DNA Test $195
Maple Syrup Urine Disease Type 1A and 1B DNA Test $195
DNA Grandfather Test $150
DNA Grandparentage Reconstruction Test $245
DNA Grandmother Test (with mother) $245
DNA Grandfather Test (with mother) $245
DNA Grandparentage Reconstruction Test (with mother) $340
DNA Grandfather Test $245
DNA Grandparentage Reconstruction Test $340
DNA Grandmother Test (with mother) $340
DNA Grandfather Test (with mother) $340
DNA Grandparentage Reconstruction Test (with mother) $435
DNA Uncle Test $150
DNA Aunt Test (with mother) $245
DNA Uncle Test (with mother) $245
Upgrade from 20 Y-DNA STR markers to 101 Y-DNA STR markers $239
Upgrade from 44 Y-DNA STR markers to 101 Y-DNA STR markers $169
*Advanced Paternal Ancestry Package (Y-DNA 44 STR Marker Test) $199
Upgrade from 67 Y-DNA STR markers to 101 Y-DNA STR markers $89
Upgrade from 91 Y-DNA STR markers to 101 Y-DNA STR markers $49
*Premium Paternal Ancestry Package (Y-DNA 101 STR Marker Test) $339
Y-DNA Haplogroup Determination SNP Test $89
Y-DNA E Subclade Panel $99
Y-DNA G Subclade Panel $99
Y-DNA H Subclade Panel $99
Y-DNA I Subclade Panel $99
Y-DNA J Subclade Panel $99
Y-DNA L Subclade Panel $99
Y-DNA N Subclade Panel $99
Y-DNA O Subclade Panel $99
Y-DNA Q Subclade Panel $99
Y-DNA R1a Subclade Panel $99
Y-DNA R1b Subclade Panel $99
Y-DNA B Subclade Panel $99
Y-DNA R2 Subclade Panel $99
Y-DNA C Subclade Panel $99
Y-DNA F Subclade Panel $99
Y-DNA K Subclade Panel $99
Y-DNA T Subclade Panel $99
*Standard Maternal Ancestry Package (mtDNA HVR1 Test) $119
*Advanced Maternal Ancestry Package (mtDNA HVR1 + HVR2 Test) $189
*Premium Maternal Ancestry Package (mtDNA HVR1 + HVR2 + Coding Region Test) $528
Add mtDNA HVR2 Test $119
Add mtDNA HVR2 + Coding Region Test $428
Add mtDNA Coding Region Test $358

All orders received before 3pm PST / 6pm EST are shipped out the same business day. All orders received after 3pm PST / 6pm EST or on weekends or holidays are shipped out the following business day. 24/7 online status check and account management available for all tests.

The Alzheimer’s Disease DNA Test Results Report

Alzheimer’s disease is a progressive brain disorder characterized initially by memory loss and later by the loss of thinking, reasoning and behavioural abilities. There are both early-onset and late-onset forms of Alzheimer’s disease. The late-onset form occurs in 90% of Alzheimer’s disease cases and the first symptoms generally appear after 65 years of age.

The APOE gene is the biggest genetic risk factor linked to the late-onset form of Alzheimer’s disease. The late-onset Alzheimer’s disease APOE genetic test determines the APOE alleles that an individual has inherited. These alleles indicate whether an individual has an increased lifetime risk of developing late-onset Alzheimer’s disease. To follow are all of the possible allele results and their associated risk:

Neutral (homozygous e3 / e3) A neutral result means that the person carries two copies of the APOE e3 allele. This is the most common allele and is a neutral allele, meaning there is no increased or decreased risk of Alzheimer’s with the presence of this allele. There is a 100% chance that this person will pass the neutral APOE e3 allele to the next generation and there is no chance that this person will pass the high risk e4 allele to the next generation.

Reduced Risk (homozygous e2 / e2) A reduced risk (homozygous) result means that the person has inherited two copies of the APOE e2 allele and may have a slightly reduced risk of Alzheimer’s. There is a 100% chance that this person will pass the reduced risk APOE e2 allele to the next generation and there is no chance that this person will pass the high-risk e4 allele to the next generation.

Reduced Risk (heterozygous e2 e3) A reduced risk (heterozygous) result means that the person has inherited one copy of the APOE e2 allele and one copy of the neutral APOE e3 allele. This person may have a slightly reduced risk of Alzheimer’s. There is a 50% chance that they will pass the reduced risk APOE e2 allele to the next generation and a 50% chance that they will pass the neutral APOE e3 allele to the next generation. There is no chance that this person will pass the high-risk e4 allele to the next generation.

Increased Risk (heterozygous e2 e4 or e3 e4) An increased risk (heterozygous) result means that the person has inherited one copy of the APOE e4 allele and one copy of either the APOE e2 or APOE e3 allele. This person has a 3-fold increased risk of developing Alzheimer’s. This person has a 50% chance of passing the defective gene (APOE e4 allele) to the next generation. If two heterozygous affected individuals have children, there is a 25% chance that their children will be normal, a 50% chance that their children will also be heterozygous affected, and a 25% chance that their children will inherit two defective genes and be at an even higher risk of developing Alzheimer’s. Increased Risk (homozygous e4 e4) An increased risk (homozygous) result means that the person has inherited two copies of the APOE e4 allele, one from each parent. This person has 10 – 15 times the normal risk of developing Alzheimer’s. There is a 100% chance that an affected individual with a homozygous genotype will pass the APOE e4 allele to the next generation.

Next, Getting the Alzheimer’s Disease APOE Genotyping Test »